中文名稱

【CEA】重組人癌胚抗原

英文名字

Recombinant Human Carcinoembryonic Antigen

供應(yīng)商

ProSpec

產(chǎn)品貨號(hào)

PRO-287

產(chǎn)品報(bào)價(jià)

￥800/2ug   ￥2080/10ug   ￥83720/1mg

產(chǎn)品說明書

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產(chǎn)品新聞

背景資料

Carcinoembryonic antigen （CEA） is a glycoprotein present in fetal digestive-tract tissues； it’s involved in cell adhesion. The production of CEA stops before birth. CEA is called tumor marker since its elevated levels are found in the serum from individuals with colorectal， gastric， pancreatic， lung and breast carcinomas and in heavy smokers.
There are also benign conditions that elevate CEA levels such as smoking， infection， inflammatory bowel disease， pancreatitis， cirrhosis of the liver， and some benign tumors （in the equivalent organs which have cancers with elevated CEA）. Typically， higher levels of CEA are found in men， smokers， and older individuals.
The presence of CEA assists in screening， in evaluating recurrent or disseminated disease， and in determining the success of surgical removal of malignant tumors.
CEA levels can be used as indicators of treatment success. The normal values range from 0.0 to 2.5 ng/ml of serum （from blood）， in non-smokers， a greater amount than that may be suggestive of cancer. Levels above 20 ng/ml before treatment are associated with cancer which has already metastasized. Benign conditions do not usually cause a CEA increase over 10 ng/ml.
The high levels of CEA should return to normal after successful therapy， however if during follow up there’s an elevation in CEA levels it indicates a recurrence of tumor.
Carcinoembryonic antigen family belongs to the immunoglobulin superfamily； it consists of 29 genes， 18 of which are normally expressed.

序列

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來源宿主

桿狀病毒-昆蟲細(xì)胞中重組表達(dá)

溶解建議

Sterile Filtered colourless solution. The sterile protein solution contains 10mM NaH2PO4， pH 7 and 150mM NaCl.

保存建議

CEA should be stored at 2-8℃. Please prevent freeze-thaw cycles.

其他

ProSpec 是一家全球著名細(xì)胞因子蛋白生產(chǎn)和研發(fā)的公司，具有20多年的生產(chǎn)經(jīng)驗(yàn)，專注于蛋白（重組及合成）生產(chǎn)研發(fā)。我們的核心產(chǎn)品包括：干擾素、白介素、骨蛋白、腫瘤壞死因子、成纖維生長因子、瘦素、干細(xì)胞因子、催乳素、表皮生長因子、胰島素樣生長因子、神經(jīng)生長因子、集落刺激因子、激素、酶、病毒抗原以及各種重組蛋白等。 領(lǐng)先的生產(chǎn)工藝和規(guī)模使其可以提供毫克到克級(jí)蛋白，價(jià)格優(yōu)于同類公司。絕大部分產(chǎn)品是天然成熟型蛋白，而不含有標(biāo)簽蛋白?？紤]到大部分研究者希望能更靈活地配制蛋白溶液，ProSpec-Tany絕大部分產(chǎn)品沒有添加保護(hù)劑或鹽，這就對(duì)工藝提出了更高的要求。同時(shí)，ProSpec-Tany絕大部分產(chǎn)品為凍干粉，因此易于運(yùn)輸和保存。