Zileuton NEW
| Price | $30 | $44 | $61 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Zileuton | CAS No.: 111406-87-2 |
| Purity: 99.56% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Zileuton |
| Description | Zileuton (A 64077) is a synthetic derivative of hydroxyurea with antiasthmatic properties. The leukotriene inhibitor zileuton blocks 5-lipoxygenase, which catalyzes the formation of leukotrienes from arachidonic acid; causes bronchodilation; decreases bronchial mucous secretion and edema; and may prevent or decrease the symptoms of asthma. |
| In vitro | Zileuton inhibited PGE2 production in lipopolysaccharide-stimulated human whole blood. In rat carrageenan gum-induced pleurisy, Zileuton decreased PGE2 and 6-ketoprostaglandin F1α pleural levels. In activated mouse peritoneal macrophages and macrophage J774, Zileuton significantly reduced PGE2 and 6-keto prostaglandin F1α levels. In macrophages, Zileuton inhibited PG biosynthesis by interfering with arachidonic acid release. |
| In vivo | Zileuton inhibited PGE2 production in lipopolysaccharide-stimulated human whole blood. In rat carrageenan gum-induced pleurisy, Zileuton decreased PGE2 and 6-ketoprostaglandin F1α pleural levels. In activated mouse peritoneal macrophages and macrophage J774, Zileuton significantly reduced PGE2 and 6-keto prostaglandin F1α levels. In macrophages, Zileuton inhibited PG biosynthesis by interfering with arachidonic acid release. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 75 mg/mL (317.41 mM) |
| Keywords | A64077 | Lipoxygenase | Inhibitor | Ferroptosis | A-64077 | inhibit | Abbott-64077 | Zileuton | Abbott64077 | LOX |
| Inhibitors Related | TBHQ | Acetylcysteine | Ibuprofen | Acetaminophen | Sorafenib | Curcumin | Diclofenac Potassium | L-Cystine | Paradol | Indomethacin sodium hydrate |
| Related Compound Libraries | Bioactive Compound Library | Pain-Related Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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