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VLX600 NEW

Price	$48	$77	$158
Package	5mg	10mg	25mg

Min. Order:
Supply Ability:	10g
Update Time:	2024-11-19

Product Details

Product Name: VLX600	CAS No.: 327031-55-0
Purity: 100%	Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

Name	VLX600
Description	VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent. It acts by reducing mitochondrial oxidative phosphorylation in tumor cells.
Cell Research	HCT116, HT29, SW620, HT8, DLD and RKO cells.Concentration,0.1, 1, 10, 100μM. 72 hours
In vitro	VLX600 as a drug that is preferentially active against quiescent cells in colon cancer 3-D microtissues.?The anticancer activity is associated with reduced mitochondrial respiration, leading to bioenergetic catastrophe and tumour cell death.?VLX600 shows enhanced cytotoxic activity under conditions of nutrient starvation.?Importantly, VLX600 displays tumour growth inhibition in vivo.
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice.
Solubility Information	DMSO : 8 mg/mL (25.21 mM)
Keywords	VLX600 \| iron \| VLX 600 \| HCT116 \| Autophagy \| glycolytic \| colon \| chelator \| cancer \| OXPHOS \| Mitochondrial Metabolism \| proliferation \| Inhibitor \| oxidative phosphorylation \| VLX-600 \| inhibit
Inhibitors Related	Stavudine \| Xylitol \| Myricetin \| Sodium 4-phenylbutyrate \| Hydroxychloroquine \| Guanidine hydrochloride \| Taurine \| Curcumin \| Oxyresveratrol \| Paeonol \| Naringin \| Gefitinib

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.