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Postion:Product Catalog >TUG-499
TUG-499
  • TUG-499

TUG-499 NEW

Price $48 $113 $163
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: TUG-499 CAS No.: 1206629-08-4
Purity: 99.59% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameTUG-499
DescriptionTUG-499 is a selective free fatty acid receptor 1 (FFAR1 or GPR40) agonist (EC50: 7.39). It shows higher affinity for FFAR1 or GPR40 relative to related receptors FFA2, FFA3, and the nuclear receptor PPARγ, as well as various other receptors, ion channels, and transporter proteins. TUG-499 is useful for studying Type 2 diabetes.
In vitroTUG-499 exhibits remarkable chemical stability, does not inhibit specific CYP enzymes or P-glycoprotein, and displays outstanding Caco-2 permeability. Its potent effects are observed on recombinant human FFA1 receptors as well as the INS-1E rat insulinoma cell line.[1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 22.5 mg/mL (70.28 mM)
KeywordsTUG 499 | TUG-499 | TUG499
Inhibitors RelatedPHYTOL | (S)-(+)-Ibuprofen | BADGE | Daidzein | Fenofibrate | Pioglitazone hydrochloride | 5-Aminosalicylic Acid | Benzyl nicotinate | Naringenin | Fisetin | 2,3-Butanediol | Icariin
Related Compound LibrariesNuclear Receptor Compound Library | DNA Damage & Repair Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Anti-Obesity Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | GPCR Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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