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Postion:Product Catalog >Inorganic chemistry>Inorganic salts>Metal nitrates and nitrites>Trilostane
Trilostane
  • Trilostane
  • Trilostane
  • Trilostane
  • Trilostane
  • Trilostane

Trilostane NEW

Price Get Latest Price
Package 25kg
Min. Order: 1kg
Supply Ability: 2000ton
Update Time: 2024-04-12

Product Details

Product Name: Trilostane CAS No.: 13647-35-3
EC-No.: 237-133-0 Min. Order: 1kg
Purity: 99% Supply Ability: 2000ton
Release date: 2024/04/12
Appearance: White Powder

indication

Trilostane can inhibit 3β-dehydrogenase in the process of corticosteroid synthesis, and reduce the synthesis of cortisol and aldosterone. It is clinically used in the treatment of Cushing syndrome (hypercortisolism) and primary hyperaldosteronism, but the therapeutic effect of the treatment of Cushing syndrome (hypercortisolism) is not as good as metiramone. This product also has a significant effect on reducing blood testosterone levels, which may be related to inhibiting its synthesis.

 

Treatment of advanced breast cancer

Breast cancer is the most common type of cancer in women. At present, for postmenopausal patients with hormone receptor-positive or unknown types of breast cancer, anti-estrogen drugs are recommended as the first choice in clinical treatment, and the effect of this therapy in delaying disease progression and improving survival time has been affirmed and confirmed by a large number of studies. The new drug Trolostam (trade name Modrenal), developed by biotech company Bioenvision and already on the market for the treatment of postmenopausal women whose hormone-selective cancer has spread beyond the breast, slows disease progression in two ways. In hormone-sensitive breast cancer, estrogen promotes cancer cell growth by acting on two receptors, estrogen receptor alpha acting as a cancer accelerator and estrogen receptor beta acting as a brake. Modrenal increased estrogen adsorption to estrogen receptor β, while decreased estrogen receptor alpha. It also acts on another site on the cell's DNA, AP1, to reduce cell proliferation.

Storage Condition

Keep in a cool and dry place

Transportation

By Sea or by Air(DHL/UPS/TNT/FEDEX/EMS)

Delivery Time

7-28 days

Payment

T/T, Western Union or Bitcoin

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Company Profile Introduction

Xi'an Haibo Biotechnology Co.,Ltd. is specialized in the study, production and sale of natural plant extract products,which are used in pharmaceuticaldietary supplement, food and cosmetic industries. Our company is located in Xian National High-tech Industrial Development Zone. Xian Haibo Biotech Co.,Ltd. has a number of departments including R&D, production, quality inspection, and market. The company's R&D center has a technical team specializing in research and developmentas well as advanced detection systems such as high-performance liquid chromatography, gas chromatography,and magnetic drive autoclave, experimental, pilot plant,and a number of scientific research institutions have established a good technical support relationship,with strong technical force. The company's production workshop has several plant extraction production lines, as well as advanced production equipment such as dynamic countercurrent extraction,column separatio

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