category

Drug substance: for the treatment of male erectile dysfunction

Physicochemical property

Appearance: Cialis (171596-29-5) is a white crystalline powder

Melting point :298-300°C

Specific rotation :D20 +71.0°

Boiling point :679.1±55.0 °C(Predicted)

Density :1.51± 0.1g /cm3(Predicted)

Flash point :2 ° C

Storage conditions :Sealed in dry,2-8°C

Solubility: The solubility in DMSO is 20mg/mL, clarified

Acidity coefficient (pKa):16.68±0.40(Predicted)

Form: Powder

Color: White to beige

optical activity :[α]/D +68 to +78°, c = 1 in chloroform-d

BCS Class:4

Stability: Unstable in methanol

InChI:InChI=1S/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28- 17 8,16,21,23 H/h2 -, 9-11 h2, h3 / t16-1, 21 - / m1 / s1

InChIKey:WOXKDUGGOYFFRN-IIBYNOLFSA-N

SMILES: N1C2 = C (C = CC = C2) C2C @ [C] ([H]) 3 C = O N (C) CC (= O) N3 @ H [C] (C3 = CC = C4OCOC4 = C3) C1 = 2 

USES 1:

Phosphodiesterase 5 inhibitors are used to treat erectile dysfunction in men. The second generation phosphodiesterase 5 inhibitors are used to treat bo dysfunction in men