Taccalonolide A NEW
Price | $110 |
Package | 5mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-12 |
Product Details
Product Name: Taccalonolide A | CAS No.: 108885-68-3 |
Purity: 98.16% | Supply Ability: 10g |
Release date: 2024/11/12 |
Product Introduction
Bioactivity
名稱 | Taccalonolide A |
描述 | Taccalonolide A is the first microtubule stabilizing agent to be discovered from a plant since identification of the mechanism of action of paclitaxel and it is the first natural product steroid identified to have these cellular effects,with cytotoxic and antimalarial activities. Taccalonolide A causes G2-M accumulation, Bcl-2 phosphorylation and initiation of apoptosis. Taccalonolide A is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug resistance protein 7 (MRP7), with an IC50 of 622 nM for SK-OV-3 cells. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 60 mg/ml (85.38 mM) |
關鍵字 | Microtubule/Tubulin | Apoptosis | Taccalonolide A | inhibit | Inhibitor |
相關產(chǎn)品 | Stavudine | 5-Fluorouracil | Myricetin | Meclizine dihydrochloride | Dextran sulfate sodium salt (MW 4500-5500) | Sodium 4-phenylbutyrate | L-Ascorbic acid | Metronidazole | Sorafenib | Tributyrin | Salicylic acid | Oleic acid |
相關庫 | 抗寄生蟲庫 | 經(jīng)典已知活性庫 | 稀有天然產(chǎn)物庫 | 植物來源化合物庫 | 微管靶向化合物庫 | 抗寄生蟲天然產(chǎn)物庫 | 抗感染天然產(chǎn)物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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