SP-471P NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-28 |
Product Details
| Product Name: SP-471P | CAS No.: 2768011-36-3 |
| Supply Ability: 10g | Release date: 2025/04/28 |
Product Introduction
Bioactivity
| Name | SP-471P |
| Description | SP-471P is a potent inhibitor of dengue virus (DENV) protease, exhibiting half-maximal effective concentrations (EC50) of 5.9 μM for DENV1, 1.4 μM for DENV2, 5.1 μM for DENV3, and 1.7 μM for DENV4, with a cytotoxic concentration (CC50) greater than 100 μM. Additionally, SP-471P effectively reduces DENV viral RNA synthesis [1]. |
| In vitro | SP-471P demonstrates low micromolar potency against DENV1, DENV2, DENV3, and DENV4, with EC50 values of 5.9 μM, 1.4 μM, 5.1 μM, and 1.7 μM, respectively [1]. At a concentration of 10 μM and an incubation period of 48 hours, it achieves an EC50 of 1.5 μM against ADE infection in human peripheral blood mononuclear cells [1]. Additionally, at the same concentration over a 6-54 hour period, it diminishes viral RNA synthesis in DENV2 [1], and at 30 hours post-treatment, SP-471P targets the NS3 int cleavage site in DENV2-infected Huh7 cells [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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