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Postion:Product Catalog >Seltorexant
Seltorexant
  • Seltorexant

Seltorexant NEW

Price $31 $44 $72
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-18

Product Details

Product Name: Seltorexant CAS No.: 1293281-49-8
Purity: 99.86% Supply Ability: 10g
Release date: 2024/11/18

Product Introduction

Bioactivity

名稱(chēng)Seltorexant
描述Seltorexant (JNJ-42847922) crosses the blood-brain barrier and quickly occupies OX2R binding sites in the rat brain. Seltorexant is a high-affinity and selective orexin-2 receptor antagonist (pKi: 8.0 and 8.1 for human and rat OX2R).
體內(nèi)活性Seltorexant (3-30 mg/kg; p.o.) dose-dependently causes and prolongs sleep in male Sprague-Dawley rats. The sleep-promoting effects of Seltorexant (30 mg/kg; p.o.; per day for 7 days) are maintained upon 7-day repeated dosing in rats [1].
存儲(chǔ)條件Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
溶解度DMSO : 250 mg/mL (613.59 mM), Sonication is recommended.
關(guān)鍵字Hypocretin Receptor | HCRT Receptor | Orexin Receptor (OX Receptor) | movement | barrier | JNJ 42847922 | Seltorexant | insomnia | somnolence | eye | blood-brain | inhibit | rapid | JNJ42847922 | selective | sleep | Inhibitor
相關(guān)產(chǎn)品L-368,899 hydrochloride | YNT-185 | Orexin 2 Receptor Agonist | IPSU | MK-3697 | Filorexant | DORA-22 | Orexin B, rat, mouse Acetate | OXA (17-33) acetate | PF3274167 | ACT-462206 | TCS 1102
相關(guān)庫(kù)經(jīng)典已知活性庫(kù) | 神經(jīng)退行性疾病化合物庫(kù) | 神經(jīng)信號(hào)分子庫(kù) | 膜蛋白靶向化合物庫(kù) | 抗癌臨床化合物庫(kù) | 藥物功能重定位化合物庫(kù) | 抑制劑庫(kù) | 已知活性化合物庫(kù) | GPCR靶點(diǎn)分子庫(kù) | 抗癌藥物庫(kù)

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Product name Price   Suppliers Update time
$31.00/1mg
VIP5Y
TargetMol Chemicals Inc.
2024-11-19
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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