SARS-CoV-2 3CLpro-IN-5 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: SARS-CoV-2 3CLpro-IN-5 | CAS No.: 2913186-57-7 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | SARS-CoV-2 3CLpro-IN-5 |
| Description | SARS-CoV-2 3CLpro-IN-5 is a covalent inhibitor targeting the 3C-like protease (3CLpro), with potent inhibitory activity (IC50: 3.8 nM) and 9.0% oral bioavailability (BA), used in COVID-19 research [1]. |
| In vitro | SARS-CoV-2 3CLpro-IN-5 demonstrates inhibitory activity against 3CL protease with an IC50 of 3.8 nM [1], and antiviral effects against SARS-CoV-2 variants (Alpha, Delta, Omicron BA.1, BA.2) in 293TAT cells, with EC50 values of 13.8 nM, 7.57 nM, 9.01 nM, and 17.1 nM, respectively [1]. It also shows activity against other coronaviruses: SARS-CoV (EC50 59.3 nM), MERS-CoV in 293TDPP4 cells (EC50 4.72 nM), and HCoV-OC43 (EC50 1.67 nM) [1]. |
| In vivo | SARS-CoV-2 3CLpro-IN-5, when administered orally or intravenously at dosages of 10 or 100 mg/kg, exhibits potent antiviral effects and possesses advantageous pharmacokinetic properties [1]. |
| Storage | Shipping with blue ice. |
| Inhibitors Related | Nirmatrelvir | EIDD-1931 | Remdesivir | Silymarin | Umifenovir hydrochloride | Hydroxychloroquine | Ritonavir | Chloroquine phosphate | Favipiravir | Imatinib |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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