RORγt inverse agonist 14 NEW
| Price | $1770 | $3580 | $4900 |
| Package | 5mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: RORγt inverse agonist 14 | CAS No.: 2672496-70-5 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | RORγt inverse agonist 14 |
| Description | RORγt inverse agonist 14 (8e) is a potent, selective, and orally active compound with an EC50 of 2.5 nM, demonstrating anti-inflammatory activity. It is utilized in the research of rheumatoid arthritis and psoriasis [1]. |
| In vivo | RORγt inverse agonist 14 (8e) exhibits a half-life (t 1/2) of 11 hours following intravenous (iv) injection at 1 mg/kg. When administered orally at 4 mg/kg in mice, the compound achieves a peak concentration (t max) in 2 hours, with an oral bioavailability (%F) of 101 [1]. Additionally, dosages ranging from 5 to 20 mg/kg effectively reduce arthritic scores, comparable to the murine analog of the commercially available TNF decoy receptor, etanercept [1]. |
| Storage | Shipping with blue ice. |
| Inhibitors Related | S18-000003 | T0901317 | GSK2981278 | Nobiletin | XY101 | Cholesterol | AZD-0284 | Melatonin | SR2211 | ML 209 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $94.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2024-11-19 | |
| $0.00/5g |
VIP3Y
|
Changsha Staherb Natural Ingredients Co., Ltd.
|
2022-08-15 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY