Product Details
Product Name:
RO0270608 |
CAS No.:
220846-33-3 |
Purity:
98.55% |
Supply Ability:
10g |
Release date:
2024/11/11 |
Product Introduction
Bioactivity
名稱 | RO0270608 |
描述 | RO0270608, the active metabolite of R411, is an orally active dual α4β1/α4β7 integrin antagonist with anti-inflammatory properties, useful for studying allergic inflammatory responses. |
體外活性 | In the human T-cell VCAM/anti CD3 costimulation assay, RO0270608 significantly inhibits T-cell proliferation (IC50=30 nM)[2]. |
體內(nèi)活性 | RO0270608, as a dual α4β1-α4β7 integrin antagonist, exhibits favorable pharmacokinetic parameters in vivo[1]. |
存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度 | DMSO : 8 mg/mL (15.82 mM), Sonication is recommended.
|
關(guān)鍵字 | RO-0270608 | RO 0270608 | RO0270608 |
相關(guān)產(chǎn)品 | K34c hydrochloride | Tirofiban hydrochloride monohydrate | Lifitegrast | Bestatin hydrochloride | ICAM-1-IN-1 |
相關(guān)庫 | 經(jīng)典已知活性庫 | 抗衰老化合物庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |