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Postion:Product Catalog >Ro 04-5595 free base
Ro 04-5595 free base
  • Ro 04-5595 free base

Ro 04-5595 free base NEW

Price $1520 $1980 $2500
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-04-27

Product Details

Product Name: Ro 04-5595 free base CAS No.: 194089-07-1
Supply Ability: 10g Release date: 2025/04/27

Product Introduction

Bioactivity

NameRo 04-5595 free base
DescriptionRo 04-5595 is a selective antagonist of NMDA receptors NR2B subunits. Ro 04-5595 had an EC 50 of 186 ± 32 nmol/L. Ro 04-5595 was predicted to bind the EVT-101 binding site, not the ifenprodil-binding site. Specific binding, defined with a new NR2B-specific antagonist Ro 04-5595 at 10 microM was fully inhibited by several compounds with the following rank order of affinities--Ro 25-6981 > CP-101,606 > Ro 04-5595 = ifenprodil >> eliprodil > haloperidol > spermine > spermidine > MgCl2 > CaCl2--and partially inhibited by competitive glutamate recognition site antagonists. Complementary high-resolution autoradiographic images using [3H]Ro04-5595 demonstrated strong binding in NR2B receptor-rich regions and low binding in cerebellum where NR2B concentration is low.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
KeywordsRo 04-5595 free base | Ro 04-5595 | CHC-2014 | CHC2014 | CHC 2014 | AUM-601 | AUM601 | AUM 601

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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