Product Details
Product Name:
PTACH |
CAS No.:
848354-66-5 |
Purity:
99.74% |
Supply Ability:
10g |
Release date:
2025/05/19 |
Product Introduction
Bioactivity
Name | PTACH |
Description | PTACH (Cpd 51) (NCH-51) is a SAHA-based inhibitor of human HDAC. It can potently inhibit the growth of various human Y cells (EC50: 1 to 10 μM). |
Kinase Assay | mTOR and PI3K Cellular Assays: Cellular IC50 values for mTOR are determined using p53?/? MEFs. Cells are treated with vehicle or increasing concentrations of Torin 2 for 1 h and then lyse. Phosphorylation of S6K1 Thr-389 is monitored by immunoblotting using a phospho-specific antibody. Meanwhile, cellular IC50 values for PI3Ka are determined based on phosphorylation of Akt Thr-308 in p53?/?/mLST8?/? MEFs or human PC3 cells expressing the S473D mutant of Akt1. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 55 mg/mL (140.82 mM), Sonication is recommended.
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Keywords | SAHA | PTACH | p21WAF1/CIP1 | NCH51 | NCH 51 | Inhibitor | inhibit | hyperacetylation | Human immunodeficiency virus | HIVProtease | HIV-1 | HIV Protease | HIV | Histone deacetylases | HDAC | Anti-cancer |
Inhibitors Related | Stavudine | 5-Fluorouracil | Emtricitabine | Kaempferol | Dolutegravir intermediate-1 | Sodium 4-phenylbutyrate | Dextran sulfate sodium salt (MW 4500-5500) | Lamivudine | Valproic Acid | Curcumin | Decanedioic acid | Tenofovir |
Related Compound Libraries | Histone Modification Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Cancer Cell Differentiation Compound Library | Epigenetics Compound Library | Chromatin Modification Compound Library | Hematonosis Compound Library | Anti-Viral Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
Product name |
Price |
|
Suppliers |
Update time |
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |