Product Details
| Product Name:
Prunin |
CAS No.:
529-55-5 |
| Purity:
99.52% |
Supply Ability:
10g |
| Release date:
2024/11/19 |
Product Introduction
Bioactivity
| Name | Prunin |
| Description | Prunin (Naringenin 7-0-glucoside) possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can stimulate growth of Pseudomonas aeruginosa and different Bacilllus sp. Prunin exhibits a markedly enhanced solubility compared to naringenin and naringin while maintaining the in vitro inhibition of HMG-CoA reductase. |
| In vitro | The effects of Prunin- and HG-alkyl (C4-C18) esters (0.1-100μM) on human leukemia T (Jurkat) cells viability and plasma membrane fluidity were evaluated. At this concentration, cell hyperpolarization and shrinkage were also observed. Cell plasma membrane fluidity was not affected, regardless the depths of the membrane level evaluated, but mild changes in plasma membrane hydration were found. Esterification did not affect the antioxidant capacity of Prunin and HG (0.1-10μM) against 1mM H2O2. When exposed to 1mM AAPH, P-alkyl esters retained Prunin antioxidant capacity, but HG-derivatives acted as pro-oxidants[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 25 mg/mL (57.55 mM)
|
| Keywords | HEVs | HEV | RNA | HRVs | Inhibitor | Phosphatase | infection | Enterovirus | inhibit | synthesis | Prunin | anti-diabetic | Rhinovirus | HRV |
| Inhibitors Related | EIDD-1931 | Phenytoin sodium | β-Glycerophosphate disodium salt pentahydrate | Aspirin | Vorinostat | Idoxuridine | (-)-Epicatechin gallate | Cyclosporine | PCL 016 | Cis-5-Norbornene-exo-2,3-dicarboxylic Anhydride | CaMKP Inhibitor | 4-Phenylbutyric acid |
| Related Compound Libraries | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Flavor Compound Library | Anti-Viral Compound Library | Natural Product Library | Cosmetic Ingredient Compound Library | Anti-infective Natural Product Library | Bioactive Compounds Library Max | Anti-virus Traditional Chinese Medicine Monomer Library | Food as Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$1.00/1KG |
VIP6Y
|
Career Henan Chemical Co
|
2020-01-03 |
United States