Pramocaine hydrochloride NEW
| Price | $30 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-28 |
Product Details
| Product Name: Pramocaine hydrochloride | CAS No.: 637-58-1 |
| Purity: 99.57% | Supply Ability: 10g |
| Release date: 2025/04/28 |
Product Introduction
Bioactivity
| Name | Pramocaine hydrochloride |
| Description | Pramocaine hydrochloride (Pramoxine HCl), a topical anesthetic, is served as an antipruritic. |
| In vitro | When administered to canines exhibiting dyspnea (breathing difficulty) and tremors, Pramoxine elicited specific changes in skin temperature at which the activation and suppression of panting and shivering occur. These changes are thought to be mediated by peripheral nerves that control the terminal mechanisms of thermoregulation. In studies on guinea pig ileum, Pramoxine (1.7 mM) demonstrated a lesser reduction in response to Substance P compared to its effects on responses to acetylcholine, BaCl2, and histamine. Pramoxine has been identified as having anesthetic inhibitory potency, with a pKa of 6.4 in guinea pig ileum. |
| In vivo | Pramoxine is frequently used in conjunction with Hydrocortisone, Colloidal oatmeal, Menthol, and Petrolatum. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 75 mg/mL (227.37 mM), Sonication is recommended. |
| Keywords | SodiumChannel | Sodium Channel | Pramoxine Hydrochloride | Pramoxine | Pramocaine Hydrochloride | Pramocaine hydrochloride | Pramocaine | Inhibitor | inhibit |
| Inhibitors Related | Phenytoin sodium | Procaine | Lidocaine Hydrochloride hydrate | Lidocaine | Safinamide | Valproic Acid | Lidocaine hydrochloride | L-Aspartic aicd sodium | Mebeverine hydrochloride | Amitriptyline hydrochloride | Riluzole | Benzocaine |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Sodium Channel Targeted Library | Drug Repurposing Compound Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Cosmetic Ingredient Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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