Potassium 1H-indol-3-yl sulfate NEW
| Price | $34 | $54 | $90 |
| Package | 5mg | 10mg | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-26 |
Product Details
| Product Name: Potassium 1H-indol-3-yl sulfate | CAS No.: 2642-37-7 |
| Purity: 99.71% | Supply Ability: 10g |
| Release date: 2025/05/26 |
Product Introduction
Bioactivity
| Name | Potassium 1H-indol-3-yl sulfate |
| Description | Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) is an agonist for the human Aryl Hydrocarbon Receptor (AhR), a key regulator of immune-inflammatory conditions. A metabolite of tryptophan derived from dietary protein, it is produced by intestinal bacteria and metabolized in the liver. In chronic kidney disease patients with impaired renal function, it accumulates in serum as a uremic toxin, inducing oxidative stress and accelerating disease progression. At 250 μM, it activates NF-Κb, promoting TGF-β1 and Smad3 expression in rat proximal tubular cells, which is associated with profibrotic activity. |
| Storage | store at low temperature | Pure form: -20°C for 3 years | In solvent: -80°C for 3 months | Shipping with blue ice. |
| Solubility Information | DMSO : 100 mg/mL (397.93 mM), Sonication is recommended. H2O : 50 mg/mL (198.97 mM), Sonication is recommended. |
| Keywords | Potassium 3-indoxyl Sulfate | Potassium 1H-indol-3-yl Sulfate | Potassium 1Hindol3yl sulfate | Potassium 1H indol 3 yl sulfate | Inhibitor | inhibit | Indoxyl sulfate potassium | EndogenousMetabolite | Endogenous Metabolite | AhR |
| Inhibitors Related | Sucrose | Acetaminophen | Daidzein | Guanidine hydrochloride | Fumaric acid | Ferulic Acid | L-Methionine | Formamide | Glycerol | Thymidine | Naringin | 3-Indoleacetic acid |
| Related Compound Libraries | Target-Focused Phenotypic Screening Library | Bioactive Compound Library | Natural Product Library | NO PAINS Compound Library | Anti-Fibrosis Compound Library | Natural Product Library for HTS | RO5 Drug-like Natural Product Library | Immunology/Inflammation Compound Library | Human Endogenous Metabolite Library | Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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