Patamostat HCl NEW
| Price | $195 | $465 | $679 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-15 |
Product Details
| Product Name: Patamostat HCl | CAS No.: 3031765-17-7 |
| Purity: 100% | Supply Ability: 10g |
| Release date: 2024/11/15 |
Product Introduction
Bioactivity
| 名稱 | Patamostat HCl |
| 描述 | Patamostat HCl is a highly potent and selective small molecule protease (protease) inhibitor that inhibits trypsin, fibrinolytic enzymes, and thrombin with IC50 values of 39 nM, 950 nM, and 1.9 μM, respectively.Patamostat HCl is used in the study of acute pancreatitis. |
| 體內(nèi)活性 | In rats or rabbits, Patamostat (intravenous infusion) at doses of 0.03-0.3 mg/kg or 0.3-3.0 mg/kg, respectively, reduces mortality after the induction of pancreatitis in a dose-dependent manner[1].In dogs with pancreatitis, Patamostat (intravenous infusion) at doses of 1.0-3.0 mg/kg reduces the increases of serum trypsin and lipase activities[1].In male Wistar rats, continuous infusion of Patamostat (2 mg/kg per h) improves almost all parameters, including mortality rate, serum and ascitic fluid amylase levels, plasma endotoxin and serum FDP levels, and distribution of lysosomal enzyme[2]. |
| 存儲條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 50 mg/mL (111.38 mM) |
| 關(guān)鍵字 | 114568-26-2 Free base | 114568-26-2 | Patamostat HCl |
| 相關(guān)產(chǎn)品 | PMSF | Nafamostat mesylate | Diminazene Aceturate | AEBSF hydrochloride | Leupeptin Hemisulfate | Ceritinib | Aprotinin | EDTA, Disodium Salt, Dihydrate | 2,4-Dioxaspiro(5.5)undec-8-ene, 3-(2-furanyl)- | Benzamidine hydrochloride |
| 相關(guān)庫 | 經(jīng)典已知活性庫 | 抑制劑庫 | 已知活性化合物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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