Ochratoxin α NEW
| Price | $311 | $426 |
| Package | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-10 |
Product Details
| Product Name: Ochratoxin α | CAS No.: 19165-63-0 |
| Supply Ability: 10g | Release date: 2025/06/10 |
Product Introduction
Bioactivity
| Name | Ochratoxin α |
| Description | Ochratoxin α (Ochratoxin alpha) is a degradation product of Ochratoxin A, used for studying Ochratoxin A degradation. |
| In vitro | The ROS level of Ochratoxin α (200-400 nM, 48 h) LX-2 cells was significantly increased, and the cell viability was decreased. [1] Ochratoxin α (2.0 μg/ml) significantly induced NLRP3 inflammasome activation and Caspase-1-dependent pyrodeath. The expression of proinflammatory cytokines (IL-6, TNF-α) and pyrogenic genes (GSDMD, IL-1β, IL-18) was increased and the secretion of MDCK cells was increased. [2] |
| In vivo | Ochratoxin α (200 and 1000 μg/kg orally) induced liver fibrosis in mice. [1] Mice with Ochratoxin α(1.0 and 2.0 mg/kg, intrabitoneal injection, once every two days for 14 days) showed renal histological injury and abnormal expression of renal fibrosis molecules (α-SMA, vimentin, TGF-β). Nod-like receptor protein 3 (NLRP3) inflammasome is activated and induces pyrodeath. [2] |
| Storage | store at low temperature,keep away from direct sunlight,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature. |
| Solubility Information | DMSO : 120 mg/mL (467.58 mM), Sonication is recommended. |
| Keywords | Ochratoxin α | Ochratoxin a |
| Inhibitors Related | Nortriptyline hydrochloride | Clofibric acid | Oseltamivir acid | Mycophenolate Mofetil | Clozapine N-Oxide | Monomethyl fumarate | Monobutyl Phthalate | Isonicotinic acid | Ampyrone | Tulipalin A | 4-Methylamino antipyrine | Nicotinamide N-oxide |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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