午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

Welcome to chemicalbook!
+1 (818) 612-2111
RFQ
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >NT157
NT157
  • NT157

NT157 NEW

Price $50 $129 $198
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-05-02

Product Details

Product Name: NT157 CAS No.: 1384426-12-3
Purity: 97.55% Supply Ability: 10g
Release date: 2025/05/02

Product Introduction

Bioactivity

NameNT157
DescriptionNT157 is a small molecule tyrphostin targeting IRS protein and has the potential to inhibit IGF-1R and STAT3 signaling pathways in TME cancer cells and stromal cells, resulting in decreased cancer cell survival.
In vitroNT157 treatment resulted in dose-dependent inhibition of IGF1R activation, suppression of IRS protein expression, inhibition of IGF1-induced AKT activation, but increased ERK activation in NT157-treated cells in vitro[2].
In vivoNT157 suppressed androgen-responsive growth, delayed CRPC progression of LNCaP xenografts, and suppressed PC3 tumor growth alone and in combination with docetaxel[2].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 77 mg/mL (186.78 mM), Sonication is recommended.
Ethanol : 25.83 mg/mL (62.65 mM), Sonication is recommended.
KeywordsSTAT3 | NT-157 | NT157 | NT 157 | Insulin Receptor 2 | Insulin Receptor 1 | IGF-1R | IGF1R
Inhibitors RelatedIndirubin Derivative E804 | Nifuroxazide | Fludarabine | Niclosamide | 2-(1,8-naphthyridin-2-yl)phenol | Balsalazide disodium dihydrate | CASIN | Diosgenin | Niclosamide olamine | Artesunate | Alantolactone | Stattic
Related Compound LibrariesAnti-Colorectal Cancer Compound Library | Anti-Pancreatic Cancer Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Inhibitor Library | Endocrinology-Hormone Compound Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

You may like

  • CAS:1594092-37-1

    $39.00 / 2mg

  • CAS:248922-46-5

    $57.00 / 1mg

  • CAS:361185-42-4

    $93.00 / 5mg

Recommended supplier

Product name Price   Suppliers Update time
$1.00/1g
VIP6Y
Career Henan Chemical Co
2019-12-25
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY