Norepinephrine NEW
| Price | $41 |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Norepinephrine | CAS No.: 51-41-2 |
| Purity: 99.84% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Norepinephrine |
| Description | Norepinephrine (Levophed) can stimulate apoptosis in adult rat ventricular myocytes by activation of the β-adrenergic pathway. It can up-regulate the expression of vascular endothelial growth factor, matrix metalloproteinase (MMP)-2, and MMP-9 in nasopharyngeal carcinoma tumour cells. |
| In vitro | METHODS: Adult hippocampal cells were treated with Norepinephrine (0.1-10 μM) for 10-13 days and the number of neurospheres was determined using classical neurosphere assay. RESULTS: A significant increase in the number of neurospheres was obtained at 100 nm and in the presence of 1 μM Norepinephrine, and a twofold increase in the number of neurospheres was observed in the presence of 10 μM Norepinephrine. [1] METHODS: Human pancreatic cancer cells BxPC-3 and Panc-1 were treated with Norepinephrine (10 μM) for 12-48 h. Cell viability was assayed by MTT Assay. RESULTS: Norepinephrine treatment alone significantly enhanced the viability of PDAC cells. [2] |
| In vivo | METHODS: To test in vivo activity, Norepinephrine (0.2-2 mg/kga) was administered intraperitoneally to C57BL6/J mice fed a high-fat diet once daily for two weeks. RESULTS: A subset of Norepinephrine-treated mice developed unexpected adverse events, including bladder dilatation and decreased renal perfusion due to renal discoloration. [3] |
| Storage | keep away from direct sunlight,keep away from moisture,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : < 1 mg/mL (Insoluble) DMSO : 6.25 mg/mL (36.94 mM), Sonification is recommended. 10% DMSO+90% Saline : 0.1 mg/mL (0.59 mM), Please add co-solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. |
| Keywords | Autophagy | Beta Receptor | inhibit | Levarterenol | Inhibitor | Norepinephrine | Endogenous Metabolite | Adrenergic Receptor |
| Inhibitors Related | Sucrose | Hydroxychloroquine | Daidzein | Guanidine hydrochloride | Doxycycline | Ferulic Acid | Paeonol | Glycerol | Thymidine |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Alkaloid Natural Product Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Human Endogenous Metabolite Library | Anti-Aging Compound Library | GPCR Compound Library | Food as Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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