Nonapeptide-1 NEW
| Price | Get Latest Price | ||
| Package | 1kg | 5kg | 25kg |
| Min. Order: | 0.10000000149011612kg |
| Supply Ability: | 2000kgs |
| Update Time: | 2025-03-10 |
Product Details
| Product Name: Nonapeptide-1 | CAS No.: 158563-45-2 |
| Min. Order: 0.10000000149011612kg | Purity: 98% |
| Supply Ability: 2000kgs | Release date: 2025/03/10 |
| Product Name: | Nonapeptide-1 |
| Synonyms: | L-Methionyl-L-prolyl-D-phenylalanyl-L-arginyl-D-tryptophyl-L-phenylalanyl-L-lysyl-L-prolyl-L-valinamide;Melanostatine-5;Melanostatine-5(nonpeptide-1);melanostatine;Met-Pro-D-Phe-Arg-D-Trp-Phe-Lys-Pro-Val-NH2;Melitane / Nonapeptide-1;Nonapeptide-1, Melanostatine-5, Melanostatine;Melitan |
| CAS: | 158563-45-2 |
| MF: | C61H87N15O9S |
| MW: | 1206.5 |
| EINECS: | 000-000-0 |
| Product Categories: | 158563-45-2 |
| Nonapeptide-1 Chemical Properties |
| density | 1.38±0.1 g/cm3(Predicted) |
| solubility | soluble in water(≥0.1g/ml) |
| form | Solid |
| pka | 13.32±0.46(Predicted) |
| color | white or off-white powder |
| InChIKey | KNFLNGRLKALWRF-LDXSYGEZSA-N |
| Nonapeptide-1 Usage And Synthesis |
| Description | Nonapeptide-1 is a skin lightening peptide, derived from the melanocyte stimulating hormone (MSH). It prevents the activity of tyrosine in the melanocytes, melanin synthesis inhibition and helps to even out your skin tone by lessening hyper-pigmentation. This process reduces the formation of unwanted pigmentation, allowing for the control over skin tone and brown spots. |
| Uses | A skin whitening nonapeptide. It can be applied to various kinds of whitening or spot corrective products. |
| Application | skin radiance, skin Lightening-whitening, anti-dark spot |
| Definition | Nonapeptide-1 is one skin whitening nonapeptide. It can be applied to various kinds of whitening or spot corrective products. |
| benefits | Nonapeptide-1inhibits melanin production originally induced bya-MSH.Whitening, spot-removing as well as preventing hyperpigmentation.Its recommended dosage in skin care products is 0.5~3%. |
| Biological Functions | 1. Inhibit melanin synthesis by interfering with the action of tyrosinase in melanocytes. Reduce hyperpigmentation and lighten darker areas that have been damaged by the sun and certain diseases.2. Interfer with melanocyte stimulating hormone (MSH). MSH increases during pregnancy, as a result of certain medical conditions (e.g. diabetes, Addison’s disease), and as a result of excessive sun exposure.3. Nonapeptide-1, at a concentration of 200 ug/mL, is capable of fully inhibiting the synthesis of melanin in fungi.4. At 100 micromolar concentration, nonapeptide-1 can inhibit 25-35% of tyrosinase activity in animal models and can reduce the melanin content of melanocytes by 27-43% |
| Biotechnological Applications | Nonapeptide-1 acetate salt, a peptide hormone, is a potent α-Melanocyte-stimulating hormone (α-MSH) antagonist, with an IC50 of 11 nM. Reduces synthesis of melanin and helps decrease skin pigmentation to a substantial degree[1]. |
| Side effects | May cause drowsiness, dizziness, hypotension, or a headache as side-effects when using Nonapeptide-1 Topical medicine. Patients not drink alcohol with medicines as alcohol intensifies drowsiness side-effects. |
| storage | Common storage 2-8℃, long time storage -20℃. |
Chongqing Zhihe Bio-pharmaceutical Co.,Ltd is mainly focus on cosmetics raw materials, our most competitive products are Phytosphingosine and has varity kinds of Ceramides, we are the the Chinese manufacturer of these.
Other two manufacturers are EVONK Germany and DOOSAN Korea, Chongqing Zhihe has the same quality with them and more competitive price.
With mature fermentation process, Zhihe can provide
ceramide NP1(IIIB),
ceramide NP2,
ceramide III,
ceramide AP(VI),
ceramide EOP,
other water souluble or oil soulble mixture of ceramides, ceramides lipidosome.
Chongqing Zhihe has R&D fermination team and Cosmetic formulation engineers team that can solve the application issues of customers.
Company Profile Introduction
Chongqing Zhihe Bio-pharmaceutical Co., Ltd. was established in August 2015, located at the foot of Jinyun Mountain, National University Science and Technology Park, Beibei District ,Chongqing, mainly engaged in the development and production of Synthetic biology technique chemical raw materials, R&D for fine chemicals technical services, Functional raw material of cosmetics, and products based on microbial fermentation biosynthesis technology (including enzyme preparations), and it is one of the major technology enterprises which are supported by Chongqing Government.
The company has established long-term and stable cooperative relationships with well-known scientific research institutions and universities at domestic and abroad, our company united academic exchanges and technical cooperation continuously, and we jointly conducted scientific research on key technologies, enhanced the company's scientific research strength, and provided a strong guarantee for the sustainable development of the company. At the same time, the company continues to invest huge amount of money in chemical raw materials, preparations, fine chemicals for technological research and development and industrial transformation. At present, the company has reserved Fusidic acid, Luriconazole, duloxetine, hyaluronic acid, L-fucose, phytosphingol, Valencia citroene and naringone and other projects with independent intellectual property rights and huge commercial value, and is carrying out industrialization and market development.
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China
- Since: 2015-07-09
- Address: Room 211, Block C, Science and Technology Venture Center, University Science and Technology Park, No
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+86-17782035140
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