Product Name:    Minoxidil

Synonyms:    2,4-diamino-6-piperidinopyrimidine3-n-oxide;4-pyrimidinediamine,6-(1-piperidinyl)-3-oxide;6-amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine;6-piperidino-2,4-diaminopyrimidine3-oxide;alopexil;2,6-diamino-4-(piperidin-1-yl)pyrimidin-1-ium-1-olate;alostil;lonolox

CAS:    38304-91-5

MF:    C9H15N5O

MW:    209.25

EINECS:    253-874-2

Product Categories:    Other APIs;ROGAINE;Heteroctcles;Bases & Related Reagents;Nitric Oxide Reagents;Nucleotides;API;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Potassium channel;38304-91-5;john's

Minoxidil is a peripheral vasodilator that directly relaxes vascular smooth musculature, thus, lowering systolic and diastolic pressure. Its action is linked to the activation of calcium channels. Open calcium channels cause hyperpolarization of smooth muscle cells, which in turn, reduces the flow of calcium ions into the cell, which is necessary for supporting vascular tonicity. However, when taking minoxidil, tachycardia, elevated renin secretion, and water and sodium ion retention all appear simultaneously with hypotension.