Melagatran NEW
| Price | $653 | $1520 | $1980 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-15 |
Product Details
| Product Name: Melagatran | CAS No.: 159776-70-2 |
| Purity: 98.37% | Supply Ability: 10g |
| Release date: 2024/11/15 |
Product Introduction
Bioactivity
| 名稱 | Melagatran |
| 描述 | Melagatran is an orally available, direct synthetic thrombin inhibitor that does not require endogenous cofactors other than thrombin and does not significantly interact with any other enzymes in the coagulation cascade or with the fibrinolytic enzymes. |
| 體內(nèi)活性 | METHODS: To test the hypothesis that a regimen consisting of an oral thrombin inhibitor would delay or prevent occlusive clot formation, anesthetized dogs were given melagatran (1.5, 2.5 mg/kg) via nasogastric tube, and 15 minutes later, a potent thrombogenic stimulus in the form of an anodic current (100 μA) was applied to the intimal surface of the stenotic left anterior descending coronary artery (LAD). RESULTS One of the dogs given high-dose melagatran did not develop thrombotic occlusion of the LAD during the entire 4-hour observation period. In the melagatran-treated dogs, coronary artery occlusions occurred during the observation period in 68% (low-dose) and 75% (high-dose) of the dogs.[2] |
| 存儲(chǔ)條件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 45 mg/mL (104.77 mM) |
| 關(guān)鍵字 | Melagatran |
| 相關(guān)產(chǎn)品 | Dabigatran Etexilate Mesylate | (S)-(+)-Ibuprofen | Edoxaban | AEBSF hydrochloride | Heparin sodium salt | Thrombin (MW 37kDa) | Menadione | Ozagrel | Eltrombopag Olamine | p-Hydroxycinnamic acid |
| 相關(guān)庫(kù) | 經(jīng)典已知活性庫(kù) | ReFRAME 相關(guān)化合物庫(kù) | 藥物功能重定位化合物庫(kù) | 抑制劑庫(kù) | 臨床期小分子藥物庫(kù) | 已知活性化合物庫(kù) |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $1980.00/50mg |
VIP1Y
|
TargetMol Chemicals Inc.
|
2024-10-28 | |
| $653.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-11-15 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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