OverviewMagnesium isoglycyrrhizinate (MGIG) is an organometallic compound derived from the active ingredient of licorice glabra with strong anti-inflammatory and hepatoprotective activities. It is a derivative of 18α glycyrrhizic acid and is more lipophilic than β isomers. Therefore, in vivo, it binds more easily to the target cell receptors of receptor proteins and steroid hormones, thus exerting anti-inflammatory, protective hepatocyte membranes, and improving liver function. Magnesium isoglycyrrhizinate is widely used in the treatment of inflammatory liver diseases such as chronic chemicalbook viral hepatitis to improve liver function abnormalities. UsesMagnesium isoglycyrrhizinate is a hepatocyte protectant, which has the effects of anti-inflammatory, protecting hepatocyte membrane and improving liver function. Magnesium isoglycyrrhizinate has a preventive effect on D-aminogalactose causing acute liver injury in rats, can prevent the increase of serum aminotransferases in animals, and reduce hepatocyte degeneration, necrosis and inflammatory cell infiltration. It has a therapeutic effect on chronic liver injury, reducing the inflammatory activity and fibrosis of liver tissue.