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Postion:Product Catalog >MAC-545496
MAC-545496
  • MAC-545496

MAC-545496 NEW

Price $36 $48 $59
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: MAC-545496 CAS No.: 838810-96-1
Purity: 97.41% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameMAC-545496
DescriptionMAC-545496 is a glycopeptide-resistance-associated protein R (GraR) inhibitor, is an antivirulence agent.
In vitroMAC-545496 could also serve as an antivirulence agent alone;?it attenuates MRSA virulence in Galleria mellonella larvae.?MAC-545496 inhibits biofilm formation and abrogates intracellular survival in macrophages.?Mechanistic characterization revealed MAC-545496 to be a nanomolar inhibitor of GraR, a regulator that responds to cell-envelope stress and is an important virulence factor and determinant of antibiotic resistance.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 250 mg/mL (595.39 mM), Sonication is recommended.
KeywordsBacterial | MAC-545496 | S. aureus | Antivirulence | Inhibitor | mprF | nanomolar | GraR | MAC 545496 | MRSA | survival | inhibit | biofilm | virulence | MAC545496 | β-lactam
Inhibitors RelatedNeomycin sulfate | Dehydroacetic acid sodium | Ampicillin sodium | Methyl anthranilate | Doxycycline (hyclate) | Kanamycin sulfate | G-418 disulfate | Sulfamethoxazole sodium | Metronidazole | Doxycycline | Dimethyl sulfoxide | Crystal Violet
Related Compound LibrariesBioactive Compound Library | Drug-induced Liver Injury (DILI) Compound Library | Antibiotics Library | Beta-Lactam Compound Library | Inhibitor Library | Anti-Bacterial Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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