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Postion:Product Catalog >Biochemical Engineering>Inhibitors>PI3K / Akt / mTOR>S6 Kinase Inhibitors>LY-2584702 free base
LY-2584702 free base
  • LY-2584702 free base

LY-2584702 free base NEW

Price $39 $54 $116
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: LY-2584702 free base CAS No.: 1082949-67-4
Purity: 98.72% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameLY-2584702 free base
DescriptionLY2584702 is a selective, ATP-competitive p70S6K inhibitor(IC50: 4 nM).
In vitroIn HCT116 colon cancer cells, LY2584702 inhibits phosphorylation of the S6 ribosomal protein (pS6) with IC50 of 0.1-0.24 μM[1]. Combined with EGFR inhibitor erlotinib or with the mTOR inhibitor everolimus, LY2584702 has significant synergistic effects [2].
In vivoLY2584702 (12.5 mg/kg BID), shows significant antitumor activity in both U87MG glioblastoma and HCT116 colon carcinoma xenograft models. [1]
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 1 mg/mL (2.24 mM), Heating is recommended.
KeywordsRibosomal S6 Kinase (RSK) | S6K | LY2584702 | LY-2584702 | Inhibitor | LY-2584702 free base | inhibit | LY2584702 free base | LY 2584702 free base | LY 2584702
Inhibitors Relatedα-Hydroxyglutaric Acid Lithium | L-Leucine | Capivasertib | Sapanisertib | Everolimus | Bimiralisib | Salidroside | Tacrolimus | GDC0084 | Dihydromyricetin | Sodium salicylate | Rapamycin
Related Compound LibrariesBioactive Compound Library | Pain-Related Compound Library | Kinase Inhibitor Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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