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Postion:Product Catalog >Litoxetine
Litoxetine
  • Litoxetine

Litoxetine NEW

Price $98 $229 $343
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Litoxetine CAS No.: 86811-09-8
Purity: 99.12% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameLitoxetine
DescriptionLitoxetine is a selective 5-HT uptake inhibitor and is a 5-HT3 receptor antagonist. Litoxetine acts as an antidepressant and has shown antiemetic properties in ferrets. Litoxetine (1 and 10 mg/kg i.v.) dose-dependently reduced the number of regurgitations and vomiting and delayed the onset of vomiting. Litoxetine has an affinity for brain 5HT3 receptors (Ki = 85 nM).
In vitroLitoxetine (0.3-3 microM) antagonized the high- and low-potency phases of the 5-HT curve.[1] Litoxetine (1 and 3 microM) responses to 5-MeOT were shifted to the right in a concentration-dependent manner.[1]
In vivoLitoxetine (twice daily for 4 days), a novel specific serotonin reuptake inhibitor.[2]
StorageShipping with blue ice.
Solubility InformationDMSO : 10 mg/mL (41.44 mM)
Inhibitors RelatedAlverine citrate | Dapoxetine hydrochloride | CLOZAPINE N-OXIDE | Trazodone hydrochloride
Related Compound LibrariesPain-Related Compound Library | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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