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Postion:Product Catalog >LEP(116-130)(mouse)
LEP(116-130)(mouse)
  • LEP(116-130)(mouse)

LEP(116-130)(mouse) NEW

Price $85 $133 $259
Package 1mg 2mg 5mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: LEP(116-130)(mouse) CAS No.: 258276-95-8
Purity: 100% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameLEP(116-130)(mouse)
DescriptionLeptin (116-130),mouse(C64H109N19O24S),a peptide with the sequence Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2. Leptin is an adipocyte-derived hormone that acts as a major regulator for food intake and energy homeostasis.
In vitroLEP-(116-130) (300 μM) fails to inhibit AP-OB binding and does not activate OB-Rb signal transduction in vitro[1].
In vivoAdministration of LEP-(116-130) (1 mg, i.p.) results in decreased body weight gain, even with increased food consumption relative to vehicle-injected control mice. It significantly reduces blood glucose levels by approximately 100 mg/dL. However, in wild-type (+/+) C57BLKS/J-m mice, LEP-(116-130) does not affect thermoregulation over 4 or 7 days[1].
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 10 mM
KeywordsLEP(116-130)(mouse) | Inhibitor | LEP(116130)(mouse) | LEP | inhibit | LEP(116 130)(mouse)
Related Compound LibrariesBioactive Compound Library | Peptide Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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