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Postion:Product Catalog >API>Antiallergic drugs>Allergic Reactions>Ketotifen fumarate
Ketotifen fumarate
  • Ketotifen fumarate
  • Ketotifen fumarate
  • Ketotifen fumarate

Ketotifen fumarate

Price Get Latest Price
Package 1kg 5kg 10kg
Min. Order: 1kg
Supply Ability: 1000
Update Time: 2025-01-16

Product Details

Product Name: Ketotifen fumarate CAS No.: 34580-14-8
Min. Order: 1kg Purity: 98
Supply Ability: 1000 Release date: 2025/01/16

Product Name:    Ketotifen fumarate

Synonyms:    Ketotifene fumarate;10H-Benzo4,5cyclohepta1,2-bthiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-, (2E)-2-butenedioate (1:1);zaditor;KETOTIFEN FUMARATE EP;Allerkif;Anatifen;4,9-Dihydro-4-(1-methyl-4-piperidylidene)-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one fumarate;zaditen

CAS:    34580-14-8

MF:    C23H23NO5S

MW:    425.5

EINECS:    252-100-0

Product Categories:    Antagonists;Histaminergics;Neurotransmitters;Histamine receptor;Aromatics;Antiallergic agents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Pharmaceutical raw material;SERC;Other APIs;API

Ketotifen is a histamine H1 receptor antagonist (Ki = 1.3 nM) and mast cell stabilizer. It is selective for H1 receptors over H2 and H3 receptors (Kis = 987 and 2,500 nM, respectively). Ketotifen (50 and 100 μM) inhibits degranulation of rat peritoneal mast cells induced by compound 48/80 . It inhibits the passive cutaneous anaphylaxis (PCA) reaction in rats by 54.6% when administered orally at a dose of 20 mg/kg. Ketotifen (30 mg/kg) inhibits the quick phase airway response in a rat ovalbumin-induced immediate airway response model. Formulations containing ketotifen have been used in the treatment of itching associated with allergic conjunctivitis.


Company Profile Introduction

Wuhan Circle Star Chem-medical Technology Co.,Ltd is located in wuhan, the central city of China, the core of the Changjiang river economic belt and known as the "thoroughfare of nine provinces".Mainly engaged in electronic chemicals, pharmaceutical intermediates, pesticide intermediates, ultraviolet absorbent, food additives and other fine chemical products research and development, production, sales and operation or agency of various products and technology import and export business. The company has two laboratories (located in wuhan and ningbo), a Chinese workshop (located in wuhan), and two amplification production bases (located in zhejiang and hubei).The company employs a number of postdocs, doctors and professors from wuhan university, huazhong agricultural university, huazhong university of science and technology and other famous universities in China to form the r&d team, and also has its own excellent sales team. The company always adhere to the "technology first, customer first, quality after-sales service" professional philosophy and enterprise spirit.The company can provide excellent products, technical support and perfect after-sales service, and ensure the quality and timely delivery regardless of business size.In order to establish a good reputation among domestic and foreign customers.

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  • Address: Room 02-31, 13 / F, Building 9, Guannan Fuxing Medical Park Phase II, No.58, Guanggu Avenue, East La
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