JNJ-1661010 NEW
| Price | $39 | $86 | $137 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: JNJ-1661010 | CAS No.: 681136-29-8 |
| Purity: 99.97% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | JNJ-1661010 |
| Description | JNJ-1661010 (Takeda-25) is an effective and specific FAAH inhibitor (IC50: 10/ 12 nM for rat/human), shows >100-fold selectivity for FAAH-1 than FAAH-2. |
| In vitro | Preincubation of JNJ-1661010 with fatty acid amide hydrolase showed a slow reversible interaction between JNJ-1661010 and the active site, which was catalyzed by high temperature. In the hydrophobic channel, JNJ-1661010 could dock with phenylthiadiazole, and in the hydrophilic pocket of fatty acid amide hydrolase, it docked with phenylurea. |
| In vivo | Preincubation of JNJ-1661010 with fatty acid amide hydrolase showed a slow reversible interaction between JNJ-1661010 and the active site, which was catalyzed by high temperature. In the hydrophobic channel, JNJ-1661010 could dock with phenylthiadiazole, and in the hydrophilic pocket of fatty acid amide hydrolase, it docked with phenylurea. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Ethanol : 3.7 mg/mL (10 mM) DMSO : 36.6 mg/mL (100 mM) |
| Keywords | broad-spectrum | acid | inhibit | hydrolase | barrier | FAAH | Takeda25 | Fatty acid amide hydrolase | amide | Takeda 25 | blood-brain | Inhibitor | JNJ-1661010 | analgesics | Fatty |
| Inhibitors Related | WWL 154 | VU534 | Biochanin A | 2-Chlorophenylboronic acid | AA38-3 | Carprofen | Dual FAAH/sEH-IN-1 | FAAH inhibitor 1 | PDP-EA | PF 750 | MM-433593 | JNJ-42165279 |
| Related Compound Libraries | Highly Selective Inhibitor Library | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Anti-Obesity Compound Library | CNS-Penetrant Compound Library | Inhibitor Library | Lipid Metabolism Compound Library | Bioactive Compounds Library Max | Preclinical Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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