Ionomycin NEW
| Price | $196 |
| Package | 1mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-18 |
Product Details
| Product Name: Ionomycin | CAS No.: 56092-81-0 |
| Purity: 99.54% | Supply Ability: 10g |
| Release date: 2024/11/18 |
Product Introduction
Bioactivity
| Name | Ionomycin |
| Description | Ionomycin is an calcium ionophore and an antibiotic that binds calcium ions (Ca2+). It is produced by the bacterium Streptomyces conglobatus.It is used in research to raise the intracellular calcium level (Ca2+) and as a research tool to understand Ca2+ transport across biological membranes. Ionomycin promotes apoptosis and induces the activation of protein kinase C (PKC). |
| In vitro | Ionomycin (2 μM) induced cell death in LCLC 103H cells, derived from a human large cell lung carcinoma, by inducing calpain activation promotes decrease of Bcl-2 proteins thereby triggering the intrinsic apoptotic pathway [2].Ionomycin also phosphorylate p38 MAPK by Ca2+ influx through SOCE, leading to suppression of TNF-α-induced NF-κB phosphorylation[3]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Ethanol : 90.0 mg/mL (126.9 mM), Sonication is recommended. DMSO : 90.0 mg/mL (126.9 mM), Sonication is recommended. |
| Keywords | Ionomycin |
| Inhibitors Related | Nisoldipine | Nimodipine | 2,5-Di-tert-butylhydroquinone | Diltiazem hydrochloride | Levetiracetam | L-Ascorbic acid | Lanthanum(III) chloride heptahydrate | Ethyl cinnamate | 1-Octanol | Otilonium bromide |
| Related Compound Libraries | 稀有天然產(chǎn)物庫 | 微生物天然產(chǎn)物庫 | 高通量篩選天然產(chǎn)物庫 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $127.00/1mg |
VIP3Y
|
TargetMol Chemicals Inc.
|
2024-10-28 | |
| $0.01/1KG |
VIP6Y
|
Shaanxi Dideu Medichem Co. Ltd
|
2020-05-11 | |
| $1.00/1g |
VIP6Y
|
Career Henan Chemical Co
|
2019-12-25 | |
| $1.10/1g |
VIP4Y
|
Dideu Industries Group Limited
|
2021-07-16 |
United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
INQUIRY