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Postion:Product Catalog >ICAM-1-IN-1
ICAM-1-IN-1
  • ICAM-1-IN-1

ICAM-1-IN-1 NEW

Price $195 $413 $618
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: ICAM-1-IN-1 CAS No.: 251994-14-6
Purity: 99.34% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameICAM-1-IN-1
DescriptionICAM-1-IN-1 is a potent and selective inhibitor of E-selectin (IC50 = 7 nM) and ICAM-1 (IC50 = 5 nM).
In vivoIn both a rat model of rheumatoid arthritis and a mouse model of asthma, ICAM-1-IN-1 demonstrates significant therapeutic effects. Notably, after nine days of treatment with ICAM-1-IN-1, there is a reduction in the swelling of inflamed ankles in the rat arthritis model; however, it does not exhibit efficacy during the acute phase of the condition. A 21-day regimen of ICAM-1-IN-1 at a dosage of 25 mg/kg markedly decreases ankle inflammation in arthritic rats. Additionally, this treatment leads to a notable decrease in eosinophil counts and levels of serum-soluble ICAM-1 (sICAM-1).
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (137.65 mM)
KeywordsICAM 1 IN 1 | inhibit | ICAM1IN1 | Inhibitor | ICAM-1-IN-1 | Integrin
Inhibitors RelatedCarvedilol phosphate hemihydrate | K34c hydrochloride | E7820 | Arg-Gly-Asp TFA (99896-85-2(free base)) | Tirofiban hydrochloride monohydrate | Lifitegrast | Elarofiban TFA | Cyclo(-RGDfK) | Tirofiban | Bestatin hydrochloride | RO0270608 | Gantofiban
Related Compound LibrariesBioactive Compound Library | ReFRAME Related Library | Inhibitor Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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