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Postion:Product Catalog >IC 86621
IC 86621
  • IC 86621

IC 86621 NEW

Price $32 $46 $76
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: IC 86621 CAS No.: 404009-40-1
Purity: 99.33% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameIC 86621
DescriptionIC 86621 is a selective and reversible ATP-competitive inhibitor of DNA-PK with an IC50 of 120 nM. IC 86621 increases DNA double-strand break(DSB)-induced antitumor activity with an EC50 of 68 μM for DNA-PK mediated cellular DSB repair.
In vitroIn CD4+CD45RO- T cells, IC 86621 (0 nM, 50 nM, 100 nM) protects rheumatoid arthritis T cells from apoptosis[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (225.99 mM)
KeywordsATP | Buchwald-Hartwig amination | Inhibitor | IC 86621 | IC-86621 | DSB | IC86621 | antitumor | inhibit | Apoptosis | Fries rearrangement | DNA-dependent protein kinase | DNA-PK
Inhibitors RelatedPI-3065 | Compound 401 | STL127705 | YU238259 | KU-57788 | PI3K-IN-1 | Samotolisib | Torin 1 | NU6027 | PI-103 | Onatasertib | LY294002
Related Compound LibrariesGlycolysis Compound Library | Bioactive Compound Library | Kinase Inhibitor Library | Anti-Breast Cancer Compound Library | Inhibitor Library | Anti-Prostate Cancer Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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