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Postion:Product Catalog >GW791343 dihydrochloride
GW791343 dihydrochloride
  • GW791343 dihydrochloride

GW791343 dihydrochloride NEW

Price $39 $68 $130
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: GW791343 dihydrochloride CAS No.: 1019779-04-4
Purity: 95.57% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameGW791343 dihydrochloride
DescriptionGW791343 dihydrochloride (GW791343 (HCl)) is a P2X7 allosteric modulator.
In vitroGW791343 were non-competitive inhibitors of human P2X(7) receptors.?Receptor protection studies using decavanadate and pyridoxalphosphate-6-azophenyl-2',4'-disulphonic acid (PPADS) showed that neither compound-17 nor GW791343 competitively interacted at the ATP binding site and so were probably negative allosteric modulators of the P2X(7) receptor.?GW791343 prevented the slowly reversible blockade of the human P2X(7) receptor produced by compound-17 and inhibited [(3)H]-compound-17 binding to the P2X(7) receptor suggesting they may bind to similar or interacting sites[1].
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 42 mg/mL (93.89 mM)
Keywordsinhibit | depressive disorder | Inhibitor | P2X Receptor | neurological disease | ATP | GW791343 Dihydrochloride | GW-791343 dihydrochloride | GW 791343 Dihydrochloride | GW791343 dihydrochloride | GW791343 | SCN cells | GW 791343 | GW-791343 | P2XRs | GW-791343 Dihydrochloride
Inhibitors RelatedOpiranserin hydrochloride | Aurintricarboxylic acid | (E/Z)-Sivopixant | PSB-12062 | ATP disodium salt | Oxatomide | JNJ-55308942 | JNJ-42253432 | Ivermectin | Lappaconitine | CTP disodium dihydrate | Brilliant blue G-250
Related Compound LibrariesTarget-Focused Phenotypic Screening Library | Bioactive Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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