Galanin Receptor Ligand M35 TFA NEW
| Price | $113 | $336 | $473 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Galanin Receptor Ligand M35 TFA | Purity: 99.45% |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Galanin Receptor Ligand M35 TFA |
| Description | Galanin Receptor Ligand M35 TFA is a high-affinity ligand and antagonist of the galanin receptor (Kd = 0.1 nM). |
| In vitro | Galanin Receptor Ligand M35 TFA exhibits dual effects on galanin-mediated inhibition of Forskolin-stimulated cyclic AMP production in Rin m 5F cells. At low concentrations (1 nM), co-applied with galanin (10 nM), it reverses galanin's inhibitory effect, while at higher concentrations (15 and 30 nM), it functions as a galanin receptor agonist, inhibiting cAMP production. These effects are not additive, reflecting its mixed agonist/antagonist properties due to its chimeric nature acting solely at galanin receptors[1]. |
| In vivo | Galanin Receptor Ligand M35 TFA (6 nM/10 μL; i.c.v.) enhances the performance of male Sprague-Dawley rats in the swim maze task by shortening escape latency, reducing failure rates in reaching the platform, and decreasing path length to the hidden platform[3]. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 10 mM |
| Keywords | Galanin Receptor Ligand M-35 TFA | Galanin Receptor Ligand M35 TFA |
| Inhibitors Related | HT-2157 | L 152804 | GW438014A | Peptide YY (PYY) (3-36), human | Selvigaltin | SF-22 | JNJ-31020028 | DF-1012 FA | AR-M 1896 Acetate | AC-099 hydrochloride |
| Related Compound Libraries | Peptide Compound Library | NO PAINS Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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