G6PD activator AG1 NEW
| Price | $599 |
| Package | 2mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-11 |
Product Details
| Product Name: G6PD activator AG1 | CAS No.: 421581-52-4 |
| Purity: 98.38% | Supply Ability: 10g |
| Release date: 2024/11/11 |
Product Introduction
Bioactivity
| 名稱 | G6PD activator AG1 |
| 描述 | G6PD activator AG1 is a glucose-6-phosphate dehydrogenase (G6PD) agonist that promotes glucose-6-phosphate dehydrogenase (G6PD) oligomerization to a catalytically competent form. G6PD activator AG1 reduces oxidative stress in cells and zebrafish, reduces chloroquine or diamide-induced oxidative stress in human erythrocytes, and can be used to study glucose-6-phosphate dehydrogenase deficiency. |
| 體外活性 | G6PD activator AG1 (1-5 μΜ; pre-incubated overnight) reduces the extent of hemolysis with 5 μΜ in human erythrocytes suspension (5%) exposed to either 1 mM chloroquine (CQ; 4 hours) or diamide (a GSH oxidant; 4 hours). G6PD activator AG1 increases GSH levels and reduced ROS levels together with increased G6PD activity under these drug-induced oxidative stress. [1] G6PD activator AG1 (50, 100, 250, 500, 750, 1000 nM) increases the viability by 20% and the proteolytic stability of Canton G6PD in SH-SY5Y cells. G6PD activator AG1 has no effect when G6PD was knocked down by siRNA, supporting the specificity of G6PD activator AG1 toward G6PD. [1] |
| 存儲(chǔ)條件 | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| 溶解度 | DMSO : 15 mg/mL (34.20 mM.), Sonication is recommended. |
| 關(guān)鍵字 | G-6PD activator AG1 | G6PD activator AG1 |
| 相關(guān)產(chǎn)品 | Disulfiram | Methotrexate | ALDH1A3-IN-3 | Rotenone | Mycophenolate Mofetil | Ribavirin | 4-Diethylaminobenzaldehyde | Benzyl alcohol | Isomalt | Isoniazid | Sodium Oxamate | Ivosidenib |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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