
Finerenone
Price | Get Latest Price | |
Package | 1kg | 25kg |
Min. Order: | 1kg |
Supply Ability: | 500kg |
Update Time: | 2025-03-07 |
Product Details
Product Name: Finerenone | CAS No.: 1050477-31-0 |
Min. Order: 1kg | Purity: 0.99 |
Supply Ability: 500kg | Release date: 2025/03/07 |
?? ?Product Overview?
?Finerenone? (CAS: 1050477-31-0) is a ?third-generation non-steroidal mineralocorticoid receptor antagonist (MRA)? with the molecular formula ?C??H??N?O?? and molecular weight ?378.42?. It is clinically proven to slow chronic kidney disease (CKD) progression and reduce cardiovascular risks in patients with type 2 diabetes?12. Approved under the brand name ?Kerendia??, it targets aldosterone-induced inflammation and fibrosis, making it vital in ?pharmaceutical formulations?, ?diabetic nephropathy therapy?, and ?cardiovascular research??35.
? ?Key Advantages?
?? ?High Purity?: ≥99% HPLC-certified, meeting USP/EP standards for pharmaceutical use?24.
?? ?Stability?: Stable for 24 months at -20°C (powder form) with rigorous batch consistency?14.
?? ?Clinical Impact?: Reduces CKD progression risk by 18% and cardiovascular events by 14% in trials?36.
?? ?Solubility?: DMSO-soluble (76 mg/mL), ideal for preclinical and formulation studies?17.
?? ?Applications?
?? ?Diabetic Nephropathy?: Core component of Kerendia? for managing CKD in diabetic patients?35.
?? ?Cardiovascular Protection?: Mitigates heart failure and myocardial infarction risks?36.
?? ?Research?: Explored for anti-fibrotic mechanisms in preclinical models?58.
?? ?Quality Certifications?
?? ?Compliance?: Adheres to USP/EP guidelines with impurities <0.3% and residual solvents within limits?24.
?? ?Batch Testing?: COA includes HPLC (>98%), NMR, and mass spectrometry data?25.
?? ?Market Trends?
The global CKD therapeutics market is projected to grow at ?7.2% CAGR (2025–2030)??36. Finerenone’s approval in 40+ countries and expanding clinical trials (e.g., heart failure studies) position it as a leader in non-steroidal MRAs?36.
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