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Postion:Product Catalog >Farletuzumab
Farletuzumab
  • Farletuzumab

Farletuzumab NEW

Price $372 $933 $1490
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: Farletuzumab CAS No.: 896723-44-7
Purity: > 95% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameFarletuzumab
DescriptionFarletuzumab (MORAb-003) is a humanized monoclonal antibody with a high affinity for folate receptor-α (FRα), acting as a potent inhibitor of FRα and impeding the growth of cells that overexpress this receptor, making it useful for cancer research.
In vitroIn CHO-FR cells, Farletuzumab (MORAb-003; 0-10 μg/mL) inhibits FRα-dependent cell growth and increases folate EC50 in a dose-dependent manner[1]. In IGROV-1 cells (0.1-100 μg/mL; 1 h), Farletuzumab mediates tumor cytotoxicity in vitro through complement-dependent cytotoxicity (CDC) and antibody-dependent cell-mediated cytotoxicity (ADCC)[1]. In CHO-FR cells (0-10 μg/mL), Farletuzumab inhibits the phosphorylation of proteins by Lyn kinase, a member of the src family of kinases, thereby blocking an FRα-mediated signaling pathway[1].
Storagestore at low temperature | store at -80°C | Shipping with blue ice.
KeywordsFarletuzumab
Inhibitors RelatedPemetrexed | Methotrexate | Folinic acid | Levomefolate calcium | Levoleucovorin Calcium | Trimethoprim | Folinic acid calcium | Pyrimethamine | Diaveridine | Pemetrexed disodium | Folinic Acid Calcium Salt Pentahydrate | Trimethoprim lactate

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.
2024-10-23
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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