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Postion:Product Catalog >API>Antineoplastic agents>Alkylating antineoplastic>Estramustine sodium phosphate
Estramustine sodium phosphate
  • Estramustine sodium phosphate
  • Estramustine sodium phosphate
  • Estramustine sodium phosphate

Estramustine sodium phosphate

Price Get Latest Price
Package 1g 5g 10g
Min. Order: 1g
Supply Ability: 1000
Update Time: 2025-06-09

Product Details

Product Name: Estramustine sodium phosphate CAS No.: 52205-73-9
Min. Order: 1g Purity: 98
Supply Ability: 1000 Release date: 2025/06/09

Product Name:    Estramustine sodium phosphate

Synonyms:    ESTRAMUSTINE PHOSPHATE SODIUM;-(dihydrogenphosphate),disodiumsalt;iumphosphate;Estra-1,3,5(10)-triene-3,17-diol (17beta)-, 3-[bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate), disodium salt;Estra-1,3,5(10)-triene-3,17-diol (17β)-, 3-[bis(2-chloroethyl)carbamate] 17-(dihydrogen phosphate), disodium salt;Estracyt;Estramustine phosphate disodium salt;NSC 89199

CAS:    52205-73-9

MF:    C23H33Cl2NNaO6P

MW:    544.38

EINECS:    257-735-7

Product Categories:    Active Pharmaceutical Ingredients;Intermediates;Other APIs

Estramustine phosphate is a derivative of estradiol (Item Nos. 20776 | 10006315) that contains a nor-nitrogen mustard group. Estramustine phosphate destabilizes microtubules by binding to microtubule-associated proteins (MAPs) with Kd values of 10 and 15 μM for MAP-1 and MAP-2, respectively. Estramustine induces cell cycle arrest in mitosis at the metaphase stage in DU145 and PC3 prostate cancer cells and induces apoptosis in U87MG human malignant glioma cells. The metabolites of estramustine phosphate have anti-androgenic effects. Formulations containing estramustine phosphate are used in the palliative treatment of prostate cancer.


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