午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

Welcome to chemicalbook!
+1 (818) 612-2111
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >ERCC1-XPF-IN-2
ERCC1-XPF-IN-2
  • ERCC1-XPF-IN-2

ERCC1-XPF-IN-2 NEW

Price $34 $55 $97
Package 2mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: ERCC1-XPF-IN-2 CAS No.: 1808986-37-9
Purity: 98.34% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameERCC1-XPF-IN-2
DescriptionERCC1-XPF-IN-2 is active in nucleotide excision repair, cisplatin enhancement and γH2AX assays. ERCC1-XPF-IN-2 is a potent inhibitor of ERCC1-XPF endonuclease with an IC 50 value of 0.6 μM [1].
In vitroERCC1-XPF-IN-2 (compound 13) (0-100 μM) exhibits DNase I and FEN-1 activity with IC50s of >100 μM, and shows binding kinetics with a Kd of ~30 μM. It is non-toxic to Hep-G2 cells at 10 μM and has short microsomal half-lives in mouse (23 min) and human (28 min). At 0-60 μM for 24 hours, it inhibits nucleotide excision repair (NER) with an IC50 of 15.6 μM in A375 cells and enhances cisplatin activity without toxicity. Additionally, at 10 μM for 6 hours, it delays DNA repair, indicated by an increase in γH2AX foci per cell[1].
StorageShipping with blue ice.
Solubility InformationDMSO : 225.0 mg/mL (689.8 mM)
Related Compound LibrariesBioactive Compound Library | Inhibitor Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

You may like

Recommended supplier

Product name Price   Suppliers Update time
$2500.00/100mg
VIP1Y
TargetMol Chemicals Inc.
2024-10-28
$0.00/1g
VIP1Y
Wuhan Circle Star Chem-medical Technology Co.,Ltd
2025-01-17
$1980.00/50mg
VIP3Y
TargetMol Chemicals Inc.
2024-10-23
  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
INQUIRY