EHNA hydrochloride NEW
| Price | $99 |
| Package | 2mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-08 |
Product Details
| Product Name: EHNA hydrochloride | CAS No.: 58337-38-5 |
| Supply Ability: 10g | Release date: 2025/05/08 |
Product Introduction
Bioactivity
| Name | EHNA hydrochloride |
| Description | EHNA hydrochloride is a selective inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2) and adenosine deaminase (ADA) with anticancer activity, increasing intracellular adenosine concentration in a treatment time-dependent manner. EHNA hydrochloride inhibits PHA and NaI04 mitogenesis. |
| In vitro | EHNA hydrochloride exhibits normal Michaelian kinetics of inhibition for the cyclic GMP-stimulated PDE2 activity with Hill plots near unity. EHNA hydrochloride prevents dAdo degradation and increases mitochondrial dATP levels in fibroblasts. EHNA hydrochloride completely ablates the ability of cyclic GMP to activate PDE2 activity, whilst having a much smaller inhibitory effect on the unstimulated PDE2 activity. [2] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | H2O : 80 mg/mL (254.92 mM.), Sonication is recommended. DMSO : 60 mg/mL(191.19 mM.), Sonication is recommended. |
| Keywords | PDE2 | InfluenzaVirus | Influenza Virus | hPDE2A | EHNA Hydrochloride | Adenosinedeaminase | Adenosine deaminase | Adenosine Deaminase |
| Inhibitors Related | Acetylcysteine | α-Vitamin E | Nitazoxanide | Curcumin | Theobromine | Apremilast | Naringenin | Salcomine | Crystal Violet | Doxofylline | Sildenafil citrate | β-Cyclodextrin |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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