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Postion:Product Catalog >DOPE
DOPE
  • DOPE

DOPE NEW

Price $97
Package 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: DOPE CAS No.: 4004-05-1
Purity: 97.23% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameDOPE
DescriptionDOPE (DOPE) is a neutral helper lipid for cationic liposomes.It is used in combination with cationic phospholipids to increase efficiency during DNA transfection studies as a non-viral method of gene delivery.
In vitroEach siRNA is encapsulated in LNP (cationic lipid-A: PEG2000-DMPE: DOPE = 47.8: 5.18: 47.1 molar percent). With the neutral lipid for the LNP is DOPE, LNP exerts knock-down (KD) effect on macrophages and DCs and Liposome-containing DOPE shows fusogenicity. LNP/siRNA significantly suppresses CD45 protein expression at an inhibition rate of 30% on macrophages and DCs but not on monocytes, neutrophils, plasmacytoid DCs, or B cells.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : <1 mg/mL (insoluble or slightly soluble), Sonication is recommended.
KeywordsDNA | emulsifier | 1,2 Dioleoyl sn glycero 3 phosphoethanolamine | siRNA | dioleoylphosphatidylethanolamine | phospholipid | inhibit | knock-down | liposome | Inhibitor | cationic | 1,2Dioleoylsnglycero3phosphoethanolamine | transfection
Related Compound LibrariesBioactive Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Bioactive Lipid Compound Library | Human Metabolite Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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  • Since: 2011-01-07
  • Address: 36?Washington?Street, Wellesley?Hills
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