Diloxanide furoate NEW
| Price | Get Latest Price | $42 | $59 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Diloxanide furoate | CAS No.: 3736-81-0 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Diloxanide furoate |
| Description | Diloxanide furoate (Dichlofurazol) is an antiprotozoal compound with oral activity that can be used in the study of amoebas in tissues and several other protozoal infections. |
| In vitro | Diloxanide furoate showed significant activity against different strains of Tissue Lysing Ameba in the concentration range of 1.95 to 2.5 μg/ml. The minimum inhibitory concentration (MIC) was 2.5 μg/ml, 2.5 μg/ml and 1.95 μg/ml for BYso strain co-cultivated with bacteria, SFL3 strain co-cultivated with Trypanosoma cruzi and SFL3 strain cultured aseptically. [1] |
| In vivo | Diloxanide furoate administered orally at doses ranging from 75-200 mg/kg once daily for 3 consecutive days showed efficacy in weanling pups at different doses. Administered at a dose of 200 mg/kg, 100% of the subject rats were cured and no amebic lesions were observed in the cecum. In addition, the cure rate was 85%, 77% and 44.4% when administered at doses of 150 mg/kg, 100 mg/kg and 75 mg/kg, respectively. The half effective dose (ED50) of the drug in rats was 77.9 mg/kg. [1] |
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Ethanol : 10 mg/mL (30.47 mM), Sonication is recommended. H2O : < 0.1 mg/mL (insoluble) DMSO : 40 mg/mL (121.9 mM), Sonication is recommended. |
| Inhibitors Related | Picaridin | Kaempferol | Kojic acid | Hydroxychloroquine | Metronidazole | Nitazoxanide | Doxycycline | Chloroquine phosphate | Diethyltoluamide | Artemisinin | Benzyl benzoate | DL-Methionine |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
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