Didanosine NEW
| Price | $33 | $51 | $68 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Didanosine | CAS No.: 69655-05-6 |
| Purity: 99.81% | Supply Ability: 10g |
| Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Didanosine |
| Description | Didanosine (ddI) is a nucleoside reverse transcriptase inhibitor analog of adenosine (IC50: 0.49 μM). |
| In vivo | In cultured human muscle cells, Didanosine induced accumulation of cytoplasmic lipid droplets, increased lactate production, and decreased SDH (part of complex II) and COX (complex IV) activity. In HIV target cells, Didanosine was converted to its active form, deoxyadenosine-5'-triphosphate (ddATP). In dissociated DRG cells in culture, Didanosine dose-dependently induced reductions in the number of neurites, the length of each neurite in the longest neurite, and the total length of the neurite. In dissociated DRG neurons, Didanosine dose-dependently induced neurite retraction or axon loss, suggesting that desipramine is useful in the development of peripheral neuropathy. In cultured human TK6 lymphoblastoid cells, Didanosine induced mutagenicity of the thymidine kinase gene induced by zidovudine. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | Ethanol : < 1 mg/mL (insoluble or slightly soluble) DMSO : 70 mg/mL (296.32 mM), Sonication is recommended. H2O : < 1 mg/mL (insoluble or slightly soluble) |
| Keywords | antiretroviral | Human immunodeficiency virus | inhibit | IEC-6 cells | apoptosis | orally active | Reverse Transcriptase | HIV | Inhibitor | Didanosine |
| Inhibitors Related | Stavudine | Emtricitabine | Lamivudine |
| Related Compound Libraries | Bioactive Compound Library | Drug Repurposing Compound Library | Anti-Viral Compound Library | Inhibitor Library | FDA-Approved Drug Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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