
Crisaborole
Price | Get Latest Price | |
Package | 1kg | 25kg |
Min. Order: | 1kg |
Supply Ability: | 500kg |
Update Time: | 2025-03-07 |
Product Details
Product Name: Crisaborole | CAS No.: 906673-24-3 |
Min. Order: 1kg | Purity: 0.99 |
Supply Ability: 500kg | Release date: 2025/03/07 |
Crisaborole (CAS 906673-24-3)?
?? ?ChemicalBook Product Profile?
?? ?Product Overview?
?Crisaborole? (C??H??BNO?) is a ?non-steroidal PDE4 inhibitor? with a molecular weight of ?251.05 g/mol?. This ?white crystalline powder? (≥99% purity, HPLC-validated) is FDA-approved for treating ?mild-to-moderate atopic dermatitis (AD)? in patients aged 2+ years?12. By inhibiting PDE4-mediated cytokine release, it reduces inflammation and itching without hormonal side effects. Available in ?1kg/5kg/25kg? sealed packaging with ?2-year stability? under dry, room-temperature storage?.
?Google Keywords?: Crisaborole CAS 906673-24-3, PDE4 Inhibitor API Supplier, Non-Hormonal Dermatitis Treatment, GMP-Certified Pharma Raw Material
? ?Key Advantages?
?? ?Non-Hormonal Safety?
Zero systemic absorption | Ideal for pediatric and long-term use?12.
?? ?High Purity & Stability?≥99% purity (HPLC/NMR validated) | Stable for ?2 years? under standard storage?34.
?? ?Targeted Efficacy?IC50 of ?0.49 μM for PDE4 inhibition? | Reduces TNF-α, IL-2, and IFN-γ cytokines?17.
?? ?Application Fields?
?Dermatology?: Core API for topical ointments (e.g., 2% or 5% formulations) targeting AD and eczema?12.
?Clinical Trials?: Key compound in anti-inflammatory drug development and pediatric AD research?37.
?Global API Supply?: Bulk production for pharmaceutical manufacturers?45.
?? ?Quality Certifications?
?Testing Methods?: HPLC, NMR, mass spectrometry, microbial limit testing?34.
?Certifications?: ?GMP?, ?ISO 9001?, and ?ICH stability guidelines? compliance?25.
?? ?Market Trends?
The ?global atopic dermatitis market? is projected to reach ?$12.5 billion by 2030?, growing at ?7.8% CAGR?. Crisaborole holds ?15% of the PDE4 inhibitor segment?, with Asia-Pacific (China, India) leading API production and export?13.
?? ?Contact us for COA, bulk pricing, and custom synthesis!
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- Since: 2018-06-08
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