
Clavulanic Acid NEW
Price | $39 | $55 | Get Latest Price |
Package | 10mg | 25mg | 50mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-05-24 |
Product Details
Product Name: Clavulanic Acid | CAS No.: 58001-44-8 |
Purity: 98.25% | Supply Ability: 10g |
Release date: 2025/05/24 |
Product Introduction
Bioactivity
Name | Clavulanic Acid |
Description | Clavulanic Acid(RX-10100), a major beta-lactam antibiotic produced by the organism Streptomyces claveris, is a potent bacterial beta-lactamase inhibitor used in the study of infections caused by bacteria. Clavulanic Acid has a broad spectrum of biological activity and is active against a wide variety of Gram-positive and Gram-negative bacteria. |
In vitro | Clavulanic acid exhibits synergistic antibacterial activity with ampicillin against microorganisms producing β-lactamase[2]. Clavulanic acid inhibits strains Ab11 and Ab51 with a minimum inhibitory concentration (MIC) ranging from 2 to 8 μg/mL[4]. |
In vivo | In C57BL/6 mice with Pseudomonas aeruginosa pneumonia, intraperitoneal injection of clavulanic acid (13 mg/kg) reduces bacterial burden in the lungs[4]. In C57BL/6 mice infected with Ab51, intraperitoneal injection of clavulanic acid (13 mg/kg) shows a half-life (t1/2) of 6.69 hours and an area under the curve (AUC) of 4.03 mg·h/L in a lung infection model[4]. In a rat model of carrageenan-induced paw edema, intraperitoneal injection of clavulanic acid (100-300 mg/kg) exhibits anti-inflammatory effects[3]. |
Storage | store at low temperature,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 10 mg/mL (50.21 mM), Sonication is recommended. |
Keywords | β-Lactamase | Fungal | Clavulanic Acid |
Inhibitors Related | Neomycin sulfate | Dehydroacetic acid sodium | Potassium gluconate | Ampicillin sodium | Doxycycline (hyclate) | Methyl anthranilate | Kanamycin sulfate | Sulfamethoxazole sodium | Doxycycline | Geraniol | Isoeugenol | Dimethyl sulfoxide |
Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Approved Drug Library | EMA Approved Drug Library | Antibiotics Library | Drug Repurposing Compound Library | Microbial Natural Product Library | Inhibitor Library | Anti-Bacterial Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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