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Postion:Product Catalog >CIQ
CIQ
  • CIQ

CIQ NEW

Price $46 $76 $148
Package 5mg 10mg 25mg
Min. Order:
Supply Ability: 10g
Update Time: 2024-11-19

Product Details

Product Name: CIQ CAS No.: 486427-17-2
Purity: 99.50% Supply Ability: 10g
Release date: 2024/11/19

Product Introduction

Bioactivity

NameCIQ
DescriptionCIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit, with EC50 values of 2.7 μM for NR2C and 2.8 μM for NR2D.
In vitroCIQ reduces associated behaviours in schizophrenia models and potentially enhances dopamine release in Parkinson's disease models. NMDA receptor CIQ increases channel opening frequency of recombinant NR2Cor NR2D containing receptors by two-fold (EC50 = 2.7 and 2.8 μM, respectively). It has no effect on NR2A or NR2B subtypes. CIQ does not alter the EC50 values for glutamate or glycine on channel opening. CIQ increases channel opening efficiency and enhances NMDA receptor responses.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 50 mg/mL (106.85 mM)
H2O : insoluble
KeywordsIonotropic glutamate receptors | Inhibitor | inhibit | iGluR | CIQ
Inhibitors Related(-)-Aspartic acid | Mephenesin | Quinolinic acid | Urethane | Halothane | Riluzole | Ifenprodil Tartrate | Bupivacaine hydrochloride monohydrate | O-Phospho-L-serine | Procaine hydrochloride | Memantine hydrochloride | UBP551
Related Compound LibrariesBioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Neuronal Signaling Compound Library | Anti-Alzheimer's Disease Compound Library | Antidepressant Compound Library | Anti-Parkinson's Disease Compound Library | Neurotransmitter Receptor Compound Library | Bioactive Compounds Library Max | Ion Channel Targeted Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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