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Postion:Product Catalog >API>Antineoplastic agents>Alkylating antineoplastic>Busulfan
Busulfan
  • Busulfan
  • Busulfan
  • Busulfan

Busulfan

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Package 1kg 5kg 10kg
Min. Order: 1kg
Supply Ability: 1000
Update Time: 2025-01-18

Product Details

Product Name: Busulfan CAS No.: 55-98-1
Min. Order: 1kg Purity: 98
Supply Ability: 1000 Release date: 2025/01/18

Product Name:    Busulfan

Synonyms:    BUSULFAN;tetramethylene bis(methanesulfonate);myleran;busulfex;busulphan;1,4-dimethanesulfonoxybutane;1,4-Bis(methyl sulfonoxy)butane;1,4-BUTANEDIOL DIMETHANESULFONATE

CAS:    55-98-1

MF:    C6H14O6S2

MW:    246.3

EINECS:    200-250-2

Product Categories:    MYLERAN;Antitumors for Research and Experimental Use;Biochemistry;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;55-98-1

Chemically, busulfan is classified as an alkyl sulfonate. One or both of the methylsulfonate ester moieties can be displaced by the nucleophilic N7 of guanine, leading to monoalkylated and cross-linked DNA. The extent of alkyl sulfonate–mediated DNA interstrand cross-linking has been shown to vary with the length of the alkyl chain between sulfonate esters, with the tetramethylene-containing busulfan showing less interstrand cross-linking capability than hexamethylene, methylene, or octamethylene analogues. Intrastrand cross-linking also occurs, preferentially at 5′-GA-3′ but also at 5′-GG-3′ sequences. Alkylation of Cys sulfhydryl groups is yet another mechanism of cytotoxicity.


Company Profile Introduction

Wuhan Circle Star Chem-medical Technology Co.,Ltd is located in wuhan, the central city of China, the core of the Changjiang river economic belt and known as the "thoroughfare of nine provinces".Mainly engaged in electronic chemicals, pharmaceutical intermediates, pesticide intermediates, ultraviolet absorbent, food additives and other fine chemical products research and development, production, sales and operation or agency of various products and technology import and export business. The company has two laboratories (located in wuhan and ningbo), a Chinese workshop (located in wuhan), and two amplification production bases (located in zhejiang and hubei).The company employs a number of postdocs, doctors and professors from wuhan university, huazhong agricultural university, huazhong university of science and technology and other famous universities in China to form the r&d team, and also has its own excellent sales team. The company always adhere to the "technology first, customer first, quality after-sales service" professional philosophy and enterprise spirit.The company can provide excellent products, technical support and perfect after-sales service, and ensure the quality and timely delivery regardless of business size.In order to establish a good reputation among domestic and foreign customers.

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  • Since: 2024-03-12
  • Address: Room 02-31, 13 / F, Building 9, Guannan Fuxing Medical Park Phase II, No.58, Guanggu Avenue, East La
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