
BSH-IN-1 NEW
Price | $118 | $297 | $469 |
Package | 1mg | 5mg | 10mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2024-11-19 |
Product Details
Product Name: BSH-IN-1 | CAS No.: 2553217-91-5 |
Purity: 98% | Supply Ability: 10g |
Release date: 2024/11/19 |
Product Introduction
Bioactivity
Name | BSH-IN-1 |
Description | BSH-IN-1 is a potent, covalent inhibitor of gut bacterial recombinant bile salt hydrolases (BSHs; IC50s: 108 nM for B. longum BSH and 427 nM for B. theta BSH). |
In vitro | BSH-IN-1 also inhibits BSH activity in growing cultures of Gram-negative (Bacteroides fragilis ATCC 25285, B. theta VPI-5482, and Bacteroides vulgatus ATCC 8482) and Gram-positive (C. perfringens ATCC 13124, Lactobacillus plantarum WCFS1, and Bifidobacterium adolescentis L2–32) bacteria. BSH-IN-1 also is a potent BSH inhibitor in growing bacterial cultures with IC50s of 237 nM and 1070 nM for B. adolescentis and B. theta, respectively. |
In vivo | In C57BL/6 mice, BSH-IN-1 (10?mg/kg; a single dose; gavage)inhibits BSH activity and can be gut-restricted. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO : 40 mg/mL (97.9 mM), Sonication is recommended. |
Keywords | BSH IN 1 | BSHIN1 | BSH-IN-1 |
Inhibitors Related | Minoxidil sulfate | Quinine sulfate dihydrate | Quinine | Hydrochlorothiazide | (±)-Naringenin | Tolbutamide | Tetraethylammonium bromide | Halothane | Butamben | Cloperastine hydrochloride | 2,2,2-Trichloroethanol | Indapamide |
Related Compound Libraries | Pain-Related Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Covalent Inhibitor Library | Fluorochemical Library | Ion Channel Targeted Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36?Washington?Street, Wellesley?Hills
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